Dr Roxanne Cooksey – Swansea University
Proton pump inhibitors (PPIs) are increasingly being prescribed for gastrointestinal digestive conditions and have revolutionised the management of stomach acid control and reflux disease.
Studies saying that the medicines used to control stomach acid can cause dementia while others saying the opposite is very confusing and can cause worry for those who are taking the medicine.
The research involved a cohort of more than 180,000 over 55-year-olds who were prescribed PPIs between 1995 and 2015. Using routine health data collected, from doctors and hospital appointments researchers set out to find out if taking certain medicines used for stomach acid problems, known as ‘proton pump inhibitors’ may be linked to developing dementia, a condition that affects the memory and ability to do usual everyday activities.
The team found that proton pump inhibitors use was not related to getting dementia. In fact, they found that those medicines were linked to a 30% less chance of getting the condition.
The research team found that medicine used to treat stomach acid conditions was not linked to dementia. The research results suggest that doctors should not be worried about people getting dementia and that those taking the medicine can feel reassured about the risk.